The first thing the ad shows is a scale. Over the soundtrack of Childish Gambino's anthem “This is America,” a narrator laments the nation’s obesity crisis and “the system” that is “built to keep us sick and stuck.” It notes the “$160 billion weight-loss industry that feeds on our failure” as images of junk cerealtmt play, pie and a cheeseburger flash across the screen.

“Something’s broken, and it’s not our bodies,” the narrator says, adding: “There are medications that work, but they’re priced for profits, not patients.”

The minute-long ad, which will run during the Super Bowl, pitches a “life-changing” solution to all this: weight-loss drugs, as offered by the telehealth startup Hims & Hers. Viewers see a fridge stocked with Hims & Hers-branded vials of medications. These are compounded drugs, meaning they haven’t gone through the traditional approval process designed to safeguard against risks to consumers — a point the ad largely glosses over.

On Friday, Senators Richard Durbin, Democrat of Illinois,ff777 casino and Roger Marshall, Republican of Kansas, sent a letter to the acting head of the Food and Drug Administration saying the ad “risks misleading patients.”

“Nowhere in this promotion is there any side-effect disclosure, risk or safety information as would be typically required in a pharmaceutical advertisement,” they wrote.

The ad has also drawn the ire of some doctors who prescribe obesity drugs, as well as the Partnership for Safe Medicines, a coalition of nonprofit organizations including some that are affiliated with the drug industry. The group sent a letter to the F.D.A. on Thursday calling the ad “dangerous” and warning it only discloses that the medications are compounded briefly and in a small font. The organization called on the Fox Corporation to withdraw the ad.

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Ms. Harris may give remarks about border issues during the visit, according to the people, who insisted on anonymity to discuss a trip that has not yet been made public. The people said final details about exactly where Ms. Harris would visit or what else she might do on the trip have not been decided. The Harris campaign did not immediately provide a comment.

“What he said or didn’t say is between him and the people of North Carolina,” said Mr. Vance, former President Donald J. Trump’s running mate. He added: “I’ve seen some of the statements. I haven’t seen them all. Some of them are pretty gross, to put it mildly. Mark Robinson says that those statements are false, that he didn’t actually speak them. So I think it’s up to Mark Robinson to make his case to the people of North Carolina that those weren’t his statements.”

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